| 03/09/1950 | RFC Malinois – R. Antwerp FC | 2 – 2 | |
| 10/09/1950 | R. Charleroi SC – RFC Malinois | 1 – 2 | |
| 17/09/1950 | RFC Malinois – RFC Brugeois | 3 – 1 | |
| 24/09/1950 | Beeringen FC – RFC Malinois | 1 – 3 | |
| 01/10/1950 | RFC Malinois – R. Beerschot AC | 4 – 2 | |
| 08/10/1950 | R. Standard Club Liègeois – RFC Malinois | 2 – 0 | |
| 15/10/1950 | RFC Malinois – ROC Charleroi | 4 – 1 | grootste zege |
| 22/10/1950 | RFC Malinois – RSC Anderlechtois | 0 – 3 | |
| 29/10/1950 | Royal Racing Club de Bruxelles – RFC Malinois | 1 – 0 | |
| 05/11/1950 | RFC Malinois – KRC Mechelen | 2 – 2 | |
| 19/11/1950 | RFC Liègeois – RFC Malinois | 3 – 0 | |
| 26/11/1950 | R. Berchem Sport – RFC Malinois | 4 – 2 | |
| 03/12/1950 | RFC Malinois – R. Daring Club de Bruxelles | 3 – 1 | |
| 10/12/1950 | R. Tilleur FC – RFC Malinois | 3 – 0 | |
| 07/01/1951 | RFC Brugeois – RFC Malinois | 2 – 1 | |
| 14/01/1951 | RFC Malinois – Beeringen FC | 2 – 1 | |
| 21/01/1951 | R. Beerschot AC – RFC Malinois | 1 – 2 | |
| 28/01/1951 | RFC Malinois – R. Standard Club Liègeois | 4 – 3 | |
| 04/02/1951 | RFC Malinois – ARA La Gantoise | 1 – 3 | |
| 11/02/1951 | ROC Charleroi – RFC Malinois | 3 – 3 | |
| 18/02/1951 | RSC Anderlechtois – RFC Malinois | 7 – 1 | grootste nederlaag |
| 25/02/1951 | RFC Malinois – Royal Racing Club de Bruxelles | 3 – 2 | |
| 11/03/1951 | KRC Mechelen – RFC Malinois | 2 – 2 | |
| 18/03/1951 | RFC Malinois – RFC Liègeois | 2 – 1 | |
| 01/04/1951 | RFC Malinois – R. Berchem Sport | 3 – 7 | |
| 08/04/1951 | R. Daring Club de Bruxelles – RFC Malinois | 3 – 2 | |
| 22/04/1951 | RFC Malinois – R. Tilleur FC | 4 – 2 | |
| 29/04/1951 | ARA La Gantoise – RFC Malinois | 3 – 2 | |
| 06/05/1951 | RFC Malinois – R. Charleroi SC | 1 – 2 | |
| 13/05/1951 | R. Antwerp FC – RFC Malinois | 0 – 0 |
| eindklassement ere-afdeling | aantal | winst | gelijk | verlies | goals+ | goals- | ptn | |
| 1 | ROYAL SPORTING CLUB ANDERLECHTOIS | 30 | 13 | 12 | 5 | 66 | 38 | 38 |
| 2 | Royal Berchem Sport | 30 | 17 | 4 | 9 | 71 | 48 | 38 |
| 3 | Koninklijke Racing Club Mechelen | 30 | 13 | 10 | 7 | 55 | 43 | 36 |
| 4 | Royal Football Club Liègeois | 30 | 13 | 9 | 8 | 65 | 41 | 35 |
| 5 | Royal Beerschot Athletic Club | 30 | 13 | 8 | 9 | 67 | 44 | 34 |
| 6 | Royal Antwerp Football Club | 30 | 13 | 8 | 9 | 54 | 52 | 34 |
| 7 | Association Royale Athlétique La Gantoise | 30 | 11 | 10 | 9 | 43 | 38 | 32 |
| 8 | Royal Standard Club Liègeois | 30 | 11 | 8 | 11 | 44 | 47 | 30 |
| 9 | Royal Olympic Club Charleroi | 30 | 12 | 5 | 13 | 60 | 60 | 29 |
| 10 | Royal Football Club Malinois | 30 | 12 | 5 | 13 | 58 | 69 | 29 |
| 11 | Royal Charleroi Sporting Club | 30 | 9 | 9 | 12 | 42 | 47 | 27 |
| 12 | Royal Racing Club de Bruxelles | 30 | 9 | 8 | 13 | 43 | 49 | 26 |
| 13 | Royal Tilleur Football Club | 30 | 9 | 8 | 13 | 41 | 48 | 26 |
| 14 | Royal Daring Club de Bruxelles | 30 | 7 | 9 | 14 | 46 | 66 | 23 |
| 15 | Beeringen Football Club | 30 | 9 | 4 | 17 | 43 | 78 | 22 |
| 16 | Royal Football Club Brugeois | 30 | 6 | 9 | 15 | 27 | 57 | 21 |